One. This number, when used figuratively, conveys the thought of singleness, uniqueness, as well as unity and agreement in purpose and action. “Jehovah our God is one Jehovah,” said Moses. (De 6:4) He alone is Sovereign. He is unique. He does not share his glory with another, as is the case with pagan trinitarian gods. (Acts 4:24; Rev 6:10; Isa 42:8) There is oneness in purpose and activity between Jehovah and Jesus Christ (Joh 10:30) and there should be complete unity of Christ’s disciples with God, with his Son, and with one another. (John 17:21; Gal 3:28) Such oneness is illustrated in the marriage arrangement.(Gen 2:24; Matt 19:6; Eph 5:28-32)
Two. The number two frequently appears in a legal setting. Agreement in the accounts of two witnesses adds to the force of the testimony. Two witnesses, or even three, were required to establish a matter before the judges. This principle is also followed in the Christian congregation. (Deut 17:6; 19:15; Matt 18:16; 2Cor 13:1; 1Tim 5:19; Heb 10:28) Doing something a second time—for example, repetition of a statement or vision, even in only a parallel way—firmly established the matter as sure and true (as in Pharaoh’s dream of the cows and the ears of grain; Gen 41:32).
Three. While the testifying of two witnesses to the same matter established proof sufficient for legal action, three made the testimony even stronger. The number three, therefore, is used at times to represent intensity, emphasis, or added strength. “A threefold cord cannot quickly be torn in two.” (Ec 4:12) Emphasis was achieved in Jesus’ threefold questioning of Peter after Peter’s three denials of Jesus. (Matt 26:34, 75; John 21:15-17) The vision telling Peter to eat of all kinds of animals, including those unclean according to the Law, was intensified by being given to him three times.
The intensity of God’s holiness and cleanness is emphasized by the declaration of heavenly creatures: “Holy, holy, holy is Jehovah.” (Isa 6:3; Rev 4:8) Before taking the last earthly king of the line of David off the throne, God said: “A ruin, a ruin, a ruin I shall make it. As for this also, it will certainly become no one’s until he comes who has the legal right, and I must give it to him.” Here he emphatically showed there would be no Davidic kings sitting upon the throne at Jerusalem in his name—the throne would be absolutely vacant—until God’s time to establish his Messiah in Kingdom power. (Eze 21:27) The intensity of woes to come to those dwelling on earth is forecast by the triple repetition of the declaration “woe.”(Rev 8:13)
Four. Four is a number sometimes expressing universalness or foursquareness in symmetry and form. It is found three times at Revelation 7:1. Here the “four angels” (all those in charge of “the four winds,” ready for complete destruction) stood on earth’s “four corners” (they could let loose the winds obliquely or diagonally, and no quarter of the earth would be spared). (Compare Dan 8:8; Isa 11:12; Jer 49:36; Zec 2:6; Matt 24:31.) The New Jerusalem is “foursquare,” equal in every dimension, being in fact cubical in shape. (Rev 21:16) Other figurative expressions using the number four are found at Zechariah 1:18-21; 6:1-3; Revelation 9:14, 15.
Six. This number at times represents imperfection. The number of “the wild beast” is 666 and is called “a man’s number,” indicating that it has to do with imperfect, fallen man, and it seems to symbolize the imperfection of that which is represented by “the wild beast.” The number six being emphasized to a third degree (the six appearing in the position of units, tens, and hundreds) therefore highlights the imperfection and deficiency of that which the beast represents, or pictures.(Rev 13:18)
Seven. Seven is used frequently in the Scriptures to signify completeness. At times it has reference to bringing a work toward completion. Or it can refer to the complete cycle of things as established or allowed by God. By completing his work toward the earth in six creative days and resting on the seventh day, God set the pattern for the whole Sabbath arrangement, from the seven-day week to the Jubilee year that followed the seven-times-seven–year cycle. (Ex 20:10; Lev 25:2, 6, 8) The “seven congregations” of Revelation, with their characteristics, give a complete picture of all the congregations of God on earth.(Rev 1:20–3:22) The “seven heads” of the “wild beast” (Rev 13:1) show the limit to which the beast would be allowed to develop.
Seventy-seven, a repetition of seven in a number, was equivalent to saying “indefinitely” or “without limit.” Jesus counsels Christians to forgive their brothers to that extent. (Matt 18:21, 22) Since God had ruled that anyone killing Cain, the murderer, must “suffer vengeance seven times,” Lamech, who apparently killed a man in self-defense, said: “If seven times Cain is to be avenged, then Lamech seventy times and seven.”(Gen 4:15, 23, 24)
Eight. The number eight was also used to add emphasis to the completeness of something (one more than seven, the number generally used for completeness), thus sometimes representing abundance. God reassured his people of deliverance from the threat of Assyria, saying that there should be raised up against the Assyrian “seven shepherds, yes, [not merely seven, but] eight dukes of mankind.” (Mic 5:5) As a fitting climax to the final festival of the sacred year, the Festival of Booths, the eighth day was to be one of holy convention, solemn assembly, a day of complete rest.(Lev 23:36, 39; Num 29:35)
Ten. Ten is a number denoting fullness, entirety, the aggregate, the sum of all that exists of something. It may be noted also that, where the numbers seven and ten are used together, the seven represents that which is higher or superior and ten represents something of a subordinate nature.
The Ten Plagues poured upon Egypt fully expressed God’s judgments upon Egypt—all that were needed to humiliate fully the false gods of Egypt and to break the hold of Egypt upon God’s people Israel. The “Ten Words” formed the basic laws of the Law covenant, the approximately 600 other laws merely enlarging on these, elucidating them, and explaining their application. (Ex 20:3-17; 34:28) Jesus used the number ten in several of his illustrations to denote entirety or the full number of something.(Matt 25:1; Luke 15:8; 19:13, 16, 17)
One of the beasts of Daniel’s vision and certain beasts described in Revelation had ten horns. These evidently represented all the powers, or “kings,” of earth making up the beastly arrangement. (Dan 7:7, 20, 24; Rev 12:3; 13:1; 17:3, 7, 12) The fullness of the test or period of test that God determines for his servants or allows them to undergo is expressed at Revelation 2:10: “Do not be afraid of the things you are about to suffer. Look! The Devil will keep on throwing some of you into prison that you may be fully put to the test, and that you may have tribulation ten days.”
Twelve. The patriarch Jacob had 12 sons, who became the foundations of the 12 tribes of Israel. Their offspring were organized by God under the Law covenant as God’s nation. Twelve therefore seems to represent a complete, balanced, divinely constituted arrangement. (Ge 35:22; 49:28) Jehovah chose 12 apostles, who form the secondary foundations of the New Jerusalem, built upon Jesus Christ. (Matt 10:2-4; Rev 21:14) There are 12 tribes of “the sons of [spiritual] Israel,” each tribe consisting of 12,000 members.(Rev 7:4-8)
(Source of information - Insight on the Scriptures, Vol 2)