Scientific evidence and logic behind the claim that the Wuhan coronavirus is man-made
3/15/2020
[Continues]
Simple and yet clear logic on how this Wuhan coronavirus may be made by the CCP
If you put the pieces together, you should be able to appreciate how easily this virus can be created by the CCP. Obviously, the starting virus template used here, either ZC45 or ZXC21, is owned only by the CCP (6). What they would do then was to modify things such that this bat coronavirus, non-infectious to humans, could be converted to a novel coronavirus that infects humans with high efficiency. They did so by following two published concepts (7, 8): 1) they converted the crucial spike protein to something that follows the scheme of the SARS spike protein so that the virus can target human ACE2; 2) they inserted a furin-cleavage site in between S1 and S2 of spike, which may make the virus more pathogenic. These two concepts are the only ones out there to get such a job done. Yet, miraculously, they are being followed precisely here. If it were mother nature who has created this virus, then mother nature must have studied recent scientific literatures very carefully and followed these key findings faithfully in her work (2, 6-8).
Also, let’s go back a little and think why they spend so much time fetching coronaviruses all over the place. Is it really like what they claimed – to understand the potentials of coronaviruses and therefore better predict future emerging coronaviruses? Why didn’t they put as much effort on vaccine research or drug discovery targeting a function/protein conserved in most coronaviruses then? The latter is not only more beneficial to the public but also way easier than predicting emerging viruses.
Another possibility, of course, is that they are collecting these things to create coronavirus-based bioweapons. What is the truth? You can make up your own mind.
As of me, I am fully convinced that this is a bioweapon made by the CCP.
Given all the facts and the logic connecting them as laid out above, it is completely reasonable to argue that, unless the CCP can prove otherwise, the world has all the right to believe that the Wuhan coronavirus was made by the CCP.
Reference
1. Daniel Wrapp NW, Kizzmekia S. Corbett, Jory A. Goldsmith, Ching-Lin Hsieh, Olubukola Abiona, Barney S. Graham, Jason S. McLellan. Cryo-EM Structure of the 2019-nCoV Spike in the Prefusion Conformation. Science. 2020.
2. Song W, Gui M, Wang X, Xiang Y. Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2. PLoS Pathog. 2018;14(8):e1007236.
3. Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020.
4. Kangpeng Xiao JZ, Yaoyu Feng, Niu Zhou, Xu Zhang, Jie-Jian Zou, Na Li, Yaqiong Guo, Xiaobing Li, Xuejuan Shen, Zhipeng Zhang, Fanfan Shu, Wanyi Huang, Yu Li, Ziding Zhang, Rui-Ai Chen, Ya-Jiang Wu, Shi-Ming Peng, Mian Huang, Wei-Jun Xie, Qin-Hui Cai, Fang-Hui Hou, Yahong Liu, Wu Chen, Lihua Xiao, Yongyi Shen. Isolation and Characterization of 2019-nCoV-like Coronavirus from Malayan Pangolins. bioRxiv. 2020.
5. Tommy Tsan-Yuk Lam MH-HS, Hua-Chen Zhu, Yi-Gang Tong, Xue-Bing Ni, Yun-Shi Liao, Wei Wei, William Yiu-Man Cheung, Wen-Juan Li, Lian-Feng Li, Gabriel M Leung, Edward C. Holmes, Yan-Ling Hu, Yi Guan. Identification of 2019-nCoV related coronaviruses in Malayan pangolins in southern China. bioRxiv. 2020.
6. Hu D, Zhu C, Ai L, He T, Wang Y, Ye F, et al. Genomic characterization and infectivity of a novel SARS-like coronavirus in Chinese bats. Emerg Microbes Infect. 2018;7(1):154.
7. Menachery VD, Yount BL, Jr., Debbink K, Agnihothram S, Gralinski LE, Plante JA, et al. A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence. Nat Med. 2015;21(12):1508-13.
8. Follis KE, York J, Nunberg JH. Furin cleavage of the SARS coronavirus spike glycoprotein enhances cell-cell fusion but does not affect virion entry. Virology. 2006;350(2):358-69.
Blog
3/15/2020
[Continues]
Simple and yet clear logic on how this Wuhan coronavirus may be made by the CCP
If you put the pieces together, you should be able to appreciate how easily this virus can be created by the CCP. Obviously, the starting virus template used here, either ZC45 or ZXC21, is owned only by the CCP (6). What they would do then was to modify things such that this bat coronavirus, non-infectious to humans, could be converted to a novel coronavirus that infects humans with high efficiency. They did so by following two published concepts (7, 8): 1) they converted the crucial spike protein to something that follows the scheme of the SARS spike protein so that the virus can target human ACE2; 2) they inserted a furin-cleavage site in between S1 and S2 of spike, which may make the virus more pathogenic. These two concepts are the only ones out there to get such a job done. Yet, miraculously, they are being followed precisely here. If it were mother nature who has created this virus, then mother nature must have studied recent scientific literatures very carefully and followed these key findings faithfully in her work (2, 6-8).
Also, let’s go back a little and think why they spend so much time fetching coronaviruses all over the place. Is it really like what they claimed – to understand the potentials of coronaviruses and therefore better predict future emerging coronaviruses? Why didn’t they put as much effort on vaccine research or drug discovery targeting a function/protein conserved in most coronaviruses then? The latter is not only more beneficial to the public but also way easier than predicting emerging viruses.
Another possibility, of course, is that they are collecting these things to create coronavirus-based bioweapons. What is the truth? You can make up your own mind.
As of me, I am fully convinced that this is a bioweapon made by the CCP.
Given all the facts and the logic connecting them as laid out above, it is completely reasonable to argue that, unless the CCP can prove otherwise, the world has all the right to believe that the Wuhan coronavirus was made by the CCP.
Reference
1. Daniel Wrapp NW, Kizzmekia S. Corbett, Jory A. Goldsmith, Ching-Lin Hsieh, Olubukola Abiona, Barney S. Graham, Jason S. McLellan. Cryo-EM Structure of the 2019-nCoV Spike in the Prefusion Conformation. Science. 2020.
2. Song W, Gui M, Wang X, Xiang Y. Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2. PLoS Pathog. 2018;14(8):e1007236.
3. Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020.
4. Kangpeng Xiao JZ, Yaoyu Feng, Niu Zhou, Xu Zhang, Jie-Jian Zou, Na Li, Yaqiong Guo, Xiaobing Li, Xuejuan Shen, Zhipeng Zhang, Fanfan Shu, Wanyi Huang, Yu Li, Ziding Zhang, Rui-Ai Chen, Ya-Jiang Wu, Shi-Ming Peng, Mian Huang, Wei-Jun Xie, Qin-Hui Cai, Fang-Hui Hou, Yahong Liu, Wu Chen, Lihua Xiao, Yongyi Shen. Isolation and Characterization of 2019-nCoV-like Coronavirus from Malayan Pangolins. bioRxiv. 2020.
5. Tommy Tsan-Yuk Lam MH-HS, Hua-Chen Zhu, Yi-Gang Tong, Xue-Bing Ni, Yun-Shi Liao, Wei Wei, William Yiu-Man Cheung, Wen-Juan Li, Lian-Feng Li, Gabriel M Leung, Edward C. Holmes, Yan-Ling Hu, Yi Guan. Identification of 2019-nCoV related coronaviruses in Malayan pangolins in southern China. bioRxiv. 2020.
6. Hu D, Zhu C, Ai L, He T, Wang Y, Ye F, et al. Genomic characterization and infectivity of a novel SARS-like coronavirus in Chinese bats. Emerg Microbes Infect. 2018;7(1):154.
7. Menachery VD, Yount BL, Jr., Debbink K, Agnihothram S, Gralinski LE, Plante JA, et al. A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence. Nat Med. 2015;21(12):1508-13.
8. Follis KE, York J, Nunberg JH. Furin cleavage of the SARS coronavirus spike glycoprotein enhances cell-cell fusion but does not affect virion entry. Virology. 2006;350(2):358-69.
Blog
