Which he spoke to the disciples, the outcome of which is the Bible. So that is rather a circular argument.
Yes, this is speaking of worldly wisdom, which leads to foolishness (Rom. 1:22). The Bible says much about godly wisdom. Why does Paul tell us to use wisdom and to walk in wisdom?
Col 3:16 Let the word of Christ dwell in you richly, teaching and admonishing one another in all wisdom, singing psalms and hymns and spiritual songs, with thankfulness in your hearts to God.
Col 4:5 Walk in wisdom toward outsiders, making the best use of the time.
Why do you think that James tells us to pray for wisdom from God and to be wise?
Jas 1:5 If any of you lacks wisdom, let him ask God, who gives generously to all without reproach, and it will be given him.
Jas 3:13 Who is wise and understanding among you? By his good conduct let him show his works in the meekness of wisdom.
Jas 3:17 But the wisdom from above is first pure, then peaceable, gentle, open to reason, full of mercy and good fruits, impartial and sincere.
Could Paul and James say those things because of what Jesus said?
Mat 22:37 And he said to him, “You shall love the Lord your God with all your heart and with all your soul and
with all your mind.
Christians are supposed to fully engage their minds in the reading and understanding of Scripture, with the help of the Holy Spirit. We are never to simply "rely on the Holy Spirit." God gave us minds for a reason, being created in his image--he will never bypass our minds, as he fully expects us to use them.
That is also why Paul made it his custom to reason with the Jews on the Sabbath (Acts 17:2, 17; 18:4, 19; 19:8-9; 24:25). Reasoning is to use logic and argument to try and persuade. It is what all believers are to do:
1Pe 3:15 but in your hearts honor Christ the Lord as holy, always being prepared to make a defense to anyone who asks you for a reason for the hope that is in you; yet do it with gentleness and respect,
So, where does the Bible teach that studying and "relying on his academic mind to learn is a waste of time," and that all we need to do is "humbly [rely] on the Holy Spirit" to be led into truth? Where are those made mutually exclusive?
Of course, this is all off-topic from what you said and I responded with:
"Before Abraham Was, I AM"