Realize this has nothing to do with the topic. I do not mean to derail the thread but could you briefly give any thoughts you might have on: 1 Timothy 5:23 Drink no longer water, but use a little wine for thy stomach's sake and thine often infirmities.
Timothy, being very well versed in the scriptures (2 Timothy 3:15) was likely violent (Matthew 11:12) with himself by means of fasting and abstinence from strong drink (Numbers 6:3), in imitation of many other holy men of the Old and New Testaments. It is not unreasonable to assume that such abstinence might have been the cause of his sickness, which is why Saint Paul suggested that he eased his labors and taken care of his health by drinking a little wine. Such moderate use of wine would have also helped him avoid the temptation to pride that follows spiritual accomplishments, very much like Saint Paul’s thorn in the flesh (2 Corinthians 12:7).
Wine, like any other of God’s creations, is not evil, drunkenness is. Having a small glass of wine doesn’t make one drunk.
Now, while the above may have been Saint Paul’s intent, it doesn’t mean that we can’t weave a spiritual contemplation around this verse - I'm guessing that is why you asked. Those who give themselves over to bodily labors for the sake of virtue (especially chastity), fuel their zeal with the warnings and threats contained in the scriptures (water) and the bitter recollection of their past sins. While this may be well and good in the heat of the battle with evil thoughts, too much of it can cause stomachache (heartache, i.e. sadness) and even despair (ailment). In that case, by focusing our mind to (drinking as it were) the mercy of God, His great love for us and the shedding of His blood (wine) for our salvation, we can ease our pain (Proverbs 31:6-7).