I think we are living in exciting times, and as the pieces fall together, I assure everyone that prophecy will be making more sense.
Of course the most obvious thing to watch for is what's happening in Israel: earlier I mentioned lunar tetrads the last two occurred around the time that Israel became a nation again, and the 1967 war where they took control of Jerusalem. The upcoming dates I'm suggesting (not adamantly sure) that it may have something to do with the temple. So we should always watch that in the middle east as they are actively planning to build it again.
Pertaining to nations and politics (and economics), there are 4 main players in the ends times as I see it. These 4 players are various confederacy of nations. When we read the book of Daniel, we see past and yet future empires culminating in the end time beast. These nations built up to what culminates as the 10-nation confederacy with the "King of the North". So that is one player, the King of the North which is what the bible says most about and is the end time Kingdom of the beast that most hear about all the time.
The second player is the King of the South and associated nations that have this ongoing conflict with the King of the North. There is a strong possibility that the middle eastern and Islamic uprisings may be paving the way for the nations of the "King of the South".
The third player you hear mentioned once in awhile, and Ezekiel devotes some chapters to is Gog and Magog and associated nations. The bible describes them coming from the Northeast, but geographically the people of these groups settled in Russia, China, the nations out in the Pacific, and I also believe South America.
Lastly, there is Israel, and by Israel I also include the lost tribe nations of NW Europe, the United States and (once called) "Commonwealth" nations that will also experience the "time of Jacob's trouble" as will the Jews in their actual homeland.
When one looks at this, there is a tendency of a crude division between the Semetic lines (excluding Israel) i.e King of the North, the Hamitic (King of the South) and Japhetic (Gog and Magog), and people ALL over the world no matter what their nationality may gravitate towards these end time groups since everyone alive today came from one of these 3 branches of Noah's sons. For example, I would expect the Mexicans to side more with the King of the South (Islamic) rather than say, Gog or Magog. But then there are exceptions such as the over religious ones may side more with the King of the North and His false prophet (church).