Cain spoke to the LORD in Genesis 4:
See Where did Cain's wife come from?.
Cain was afraid of his own relatives: brothers, sisters, nephews, nieces, etc. They might attempt revenge killing.14 "Today you are driving me from the land, and I will be hidden from your presence; I will be a restless wanderer on the earth, and whoever finds me will kill me.”
See Where did Cain's wife come from?.