Sin is not equivalent with transgression. Sin is the aftermath of transgression, the corruption of your way. You break a commandment. That's transgression. The wrong you find yourself doing because you broke the commandment is the sin. Adam and Eve found themselves sewing fig leaves because they had transgressed. Sewing and hiding among the trees entailed a debt of sin because they were diverted from their singular duty: dressing and keeping the garden. Their diversion is an expense someone will have to pay. Today the earth is an awful place because mankind is diverted from their singular purpose. You may not be transgressing a commandment because you love the Lord sufficiently. But being new creatures we are still fallen from being naked, the man and his wife, and unashamed. We are sometimes, in fact quite often, diverted from our purpose and this is sin (not the transgression).
But to answer your primary question the blood of Christ is all-powerful.