Escape? How?
God's Word does not show Christ's faithful Church physically escaping the coming "great tribulation". Lord Jesus and His Apostles showed we would be here on earth through it, and to be prepared to give a Testimony against the beast for Christ by The Holy Spirit.
The idea of OUR escaping is to escape the 'temptation' that is coming during the "great tribulation", not a physical escape...
Rev 3:10
10 Because thou hast kept the word of my patience, I also will keep thee from the hour of temptation, which shall come upon all the world, to try them that dwell upon the earth.
KJV
That's one of the verses the Pre-tribulational Rapture theory crowd tries to use as proof that we are raptured to Heaven prior to the great tribulation. Jesus actually said there He would keep His elect represented by that Church from that "hour of temptation", not to physically remove them from the earth. That "hour of temptation" represents the coming "great tribulation".
So what's the "temptation" that is to occur in that symbolic "hour"? It's this...
Matt 24:21-28
21 For then shall be great tribulation, such as was not since the beginning of the world to this time, no, nor ever shall be.
22 And except those days should be shortened, there should no flesh be saved: but for the elect's sake those days shall be shortened.
23 Then if any man shall say unto you, "Lo, here is Christ, or there"; believe it not.
24 For there shall arise false Christs, and false prophets, and shall shew great signs and wonders; insomuch that, if it were possible, they shall deceive the very elect.
25 Behold, I have told you before.
26 Wherefore if they shall say unto you, "Behold, He is in the desert"; go not forth: "behold, He is in the secret chambers"; believe it not.
27 For as the lightning cometh out of the east, and shineth even unto the west; so shall also the coming of the Son of man be.
28 For wheresoever the carcase is, there will the eagles be gathered together.
KJV
In the above, Lord Jesus is warning about the coming of a specific false-Messiah to Jerusalem for the end of this world. Right after that false Messiah shows up, the next Sign is the event of His 2nd coming and gathering of His faithful Church that waited on Him.
Thus that coming FALSE MESSIAH to Jerusalem, playing Christ (Messiah), is the TEMPTATION Lord Jesus was pointing to in Revelation 3:10. That is the "hour of temptation", and it will be about the temptation to fall away to that fake-Christ instead of WAITING on Lord Jesus to return to end the reign of the fake Jesus.
In 2 Thessalonians 2, Apostle Paul is warning us about this same event of that false Messiah in Jerusalem for the end, claiming to be God, and over all that is worshipped or even that is called... God (that means over ALL religious systems on earth, including the deceived in man's church systems.)